When we speak, co-founder Hamish Grierson describes Thriva as “a lifestyle brand with medical-grade testing at the back end”, an opportunity for “people to see themselves as consumers rather than patients”. Grierson gives examples of people who have benefited from Thriva testing, sometimes picking up early on serious issues. As for alarming people, Grierson says that Thriva has on-site facilities to discuss results and is intended to be “complementary to the NHS” rather than replacing it: “If there are questions we can’t answer, we’re very clear that people should pick it up with their GP.”
This is one of the most common questions and the most difficult to answer. There are approximately forty companies currently offering DNA testing to determine genealogy and ethnicity. None of these companies have shared their data, no standards of accuracy have been agree on and independent scientists have not yet validated these methods. Some experts believe the results are valid, others feel they must be viewed with some skepticism. Once you receive your results, you must decide on the validity based on your knowledge of your family history.
I’ve been working on my family tree for decades. When I took the AncestryDNA autosomal test, the ethnic results matched my expectations, with mild variations. I knew my mother was of completely Irish heritage, but I came up 58% Irish, so apparently some of Dad’s British ancestors were Irish, not English, for instance. The section that matched me to other DNA test-takers was also accurate. I recognized a couple of my second cousins listed there. Other people had taken the test but hadn’t created a family tree, so there was no point in contacting them to figure out which ancestors we had in common. Be sure you’ve done some research on your own family–these kits do NOT tell you where you grandparents came from, or their occupations, or their names. They tell you how much of your DNA is common with certain nations or areas. I know I have some Germanic ancestors, so when my kit said “14% West Europe” and that turned out to include Germany, France, Netherlands, Belgium, Luxemburg, and Lichtenstein, it made sense.
Findmypast & Living DNA are excited about the opportunities this partnership creates for everyone from serious genealogists to those just starting to explore their family history. As we focus on the best of British and Irish family history, we are committed to continue making improvements to the Findmypast DNA test to make it possible to not only discover where your ancestors came from, but learn their amazing stories too.
Some services include shipping costs in the cost of the kit; AncestryDNA's $99 fee includes two-way shipping. National Geographic's Genographic Project ships the kits for free, but you have to purchase postage when you send your kit to their lab. 23andMe tacks on a two-way shipping fee of $9.95 for the first kit and $5 for each additional one. HomeDNA includes a prepaid envelope to return your sample and offers three shipping options: $7 for two-day shipping, $14 for overnight, and free shipping that takes 7 to 12 business days. Finally, MyHeritage charges $12 for shipping; if you order two kits, you pay $6, and if you order three or more, you get free shipping.
If this individual used several different companies for DNA testing, they might get an idea as to their past origins based on the moderate or high similarities of the people currently living in different regions throughout Africa. This is only possible if the companies have established the correct reference populations. This person must understand their DNA is being matched to the current population as opposed to the people who occupied the region hundreds of years in the past. It is just as possible the results would state this African-American individual is 75 percent European. This is because the ancestry markers chosen are only for a small percentage of this individual’s DNA. The African population has a more genetic diversity in itself than a European population and an African population.
DNA Clinics will always advise an appointment for your DNA test. However, there are occasions and circumstances when our customers prefer to collect their own mouth swab samples for DNA testing. DNA Clinics self-collection DNA testing kits are available to order by telephone by calling 0800 988 7107 or on-line at www.homednapaternitytest.co.uk. DNA test kits ordered on-line are sent out for FREE. The payment for your chosen DNA test is payable when you return your samples to DNA Clinics.
While men can trace both their maternal haplogroup (from mitochondrial DNA) and their paternal haplogroup (through the Y chromosome passed down from their father), women can only trace their maternal haplogroup (through the mitochondrial DNA passed down from their mother). This is because the paternal haplogroup is traced through the Y chromosome, which women do not inherit.
Most direct-to-consumer DNA test companies warn that the tests may reveal things you wish you didn’t know about your family. For example, you could find out that one of the people who raised you isn’t your biological parent or that there’s an entire branch of your family you didn’t know about. There isn’t a way to prepare for a shock like that, but you can opt out of a company’s family-matching services if you’d rather not know.
HomeDNA has the simplest DNA extraction process; just swab each cheek twice with a cotton swab, and place the swabs in the included envelope. The National Geographic Genographic Project sent a scraper that you use on each cheek for 45 seconds, and then place in a vial with stabilizing liquid. MyHeritage DNA has a similar process. 23andMe and AncestryDNA require that you spit into a tube up to the fill line (harder than it sounds), and ship it back with stabilization liquid. Most of the services said not to eat, drink, or smoke for 30 minutes to an hour prior to testing to get the best possible sample.
All this comes into sharp focus with the comprehensive kits such as the one provided by 23andMe: the one I drool into a tube for (incidentally, 23andMe doesn’t test for Huntington’s disease). Most people, like myself, have a low understanding of genetic variants, what phrases such as “higher risk” or “probability” actually mean or how to interpret our results correctly. Is it right that ordinary members of the public must navigate potentially frightening and/or misleading results alone?
Hello…so I am interested in purchasing a few test for myself, my sister and my brother for Christmas. Primary interest is just seeing what our true roots are. Growing up we have been told we are Native American (Nipmuc tribe) and african american with some roots in Jamaica but I would love to see how accurate that all is. Not really looking to get “connected” to any long lost relatives but it would be great to know where in the world we “originate” from when looking into our ancestry. Which test would be the best for these results? Thank you… Read more »
A few of the DNA tests we tested, including the National Geographic Geno 2.0, use genetic sequencing instead of genotyping. Sequencing is newer in the mainstream direct-to-consumer DNA testing market, as it used to cost more and take much longer to sequence a person’s DNA. Sequencing identifies the exact makeup of a certain piece of DNA – be it a short segment or the whole genome. The Helix tests sequence the Exome, which are the parts of the genome responsible for protein production, plus several other regions of interest. DNA sequencing gives more information overall and has more uses in medical testing than genotyping. In the future, more DNA kits may move from genotyping to DNA sequencing as the technology gets cheaper and faster, but for now both are effective ways to look into your geographic ancestry.
Miscellaneous, fun DNA tests: On the not-so-serious side of at-home DNA testing, there is a company that offers wine recommendations based on your genes. Vinome is part of the Helix marketplace. It creates a personalized taste profile for you based on your genes and offers a curated list of wines you can buy through the service. If you buy and rate the wines, Vinome hones in on your preferences and matches you to new products.
Health & Wellness tests: There are a ton of health and wellness DNA tests. We found several specifically oriented to dieting and weight loss, including embodyDNA, Vitagene, DNAFit and the several options available through the Helix marketplace. While there definitely are some links between DNA and factors that contribute to weight, we advise taking these diet plans with a grain of salt, as DNA science is still a relatively young field. We similarly advise caution for the multitude of non-diet health and wellness DNA tests, which offer insights into your sleep, food sensitivities, and vitamin and mineral levels. And double that for medical information found in consumer DNA kit test results. While medical insights learned from taking an at-home DNA test may be interesting, it’s best not to take them too seriously. If you have a concern about a genetic predisposition to a disease, it’s best to talk to your doctor instead of relying on a direct-to-consumer kit.
Finally, if you happen to meet a special someone on DNA Romance and want to see what your future child together might look like, there’s BabyGlimpse by HumanCode. Like a very advanced Punnett square, BabyGlimpse compares your and your partner’s DNA to create a profile that examines which traits your offspring might inherit, including things like ancestral DNA, eye color and lactose intolerance.
Uploading my Raw AncestryDNA file to the free GedMatch service, immediately displayed my known Italian, Scottish, Welsh and English heritage along with French that I had been hoping to find to confirm a verbal family history plus Irish, German and Swedish which were a pleasant surprise that I will enjoy trying to discover which branch of the tree they belong to! I have also uploaded the DNA file to other free services, MyHeritage that also shows the Mediterranean connection along with LivingDNA whose results I am still waiting for. All these services also include cousin matches who share dna so you end up with a much bigger pool of possible matches than Ancestry alone.
The most important part of this process is registering your kit before shipping it. All five services require this, and if you don't do it, you won't be able to access your results. This requirement is to protect your privacy—your name won't appear on the kit or the results—and to easily track your kit as it goes through the process. Of course, when you sign up for an account with these services, your identity will be associated with it, but the sample and any reports stored on the service's end will just have a unique barcode.
Some of the companies providing ancestry DNA testing have an option that will reveal information regarding any individual with similar SNP’s. It is even possible to acquire a list of individuals who may be included in the ancestry of your family. Once permission has been given, they are able to contact you and you can contact them as well. This may sound entertaining and harmless at first, but raises a lot of questions about what information people may not be ready to hear. You may already know specifically where you come from. Now imagine if you found out your real mother was actually your grandmother. Perhaps you were raised as you birth mother’s sister. You have to ask yourself if you could handle that type of information. Prior to signing up for an ancestry DNA service, you must be aware of all the potential implications that may be revealed.
“My concern is that more and more of these tests are being put out, and people are being persuaded to have these tests done, and they get results back that are very often of very low value and dubious helpfulness,” she says. “And often people are told to go to see their GP and that then places a direct stress on the NHS, at no cost to the company. The companies make their profits and walk away, letting the NHS sort out all the fallout, the push-back, from the test results, in a way I find absurd. Why should the NHS have to prop up the problems that these companies create?”