The 100,000 Genomes Project is an NHS initiative, run by Genomics England, and is the largest national genome sequencing project in the world. On entering, patients have their entire genome, of more than 3bn base pairs, sequenced. This is different from commercially available genetic testing kits, such as those from 23andMe, which only look at very small stretches of DNA in a process called genotyping. The hope of the NHS is that having so much genetic information, from so many different people, will allow “groundbreaking discoveries about how diseases work, who could be susceptible to them, how we can treat them, and what treatments might work”.
In McCartney’s view, enough testing is already done in this country (sometimes too much) and there are issues of regulation and “informed consent”. “People are given very dramatic reasons to have these tests – it could help save your life, it could help improve the quality of your life – but where is the actual controlled evidence that these tests have ever done that? There’s no evidence that says doing these tests makes people become healthier.”
I would like to know about the paternal side of my father’s family. My problem is that there are no living males. (My father’s sister had a son that is still living, however, if he does a Y-dna test I believe that will only give out HIS father’s information). I wonder if I should have this male cousin take the mtDNA test instead. That way I could at least find out more about the maternal side of my father’s family. Any advice?

If you’ve always wondered about where your roots stem from but never knew how or where to find out, we’re here to tell you that the search is finally over! With DNA testing being easily accessible for all, the answers to your ancestry questions will soon be revealed. A simple DNA test can be completed from the comforts of your own home and will open your eyes to the mysteries of your family tree, once and for all. We have tested the best DNA tests for ancestry and gathered all the available information so you would be able to get the best decision on the journey to discover the realm of your genetic heritage. We recommend MyHeritage as the best Ancestry DNA test available.

We constantly strive to improve our service and keep up to date with the latest developments in this area, so you always receive the highest quality of results. Our non invasive prenatal paternity test is a one-of–a-kind test that makes it clear who the daddy is with 0% risk at only 10 weeks of pregnancy. Through us, you have access to a whole range of relationship tests, forensic services, health and clinical tests and never need to go anywhere else. So what is it you need to know? Just tell us what you want to establish, provide us with your DNA samples and we will provide the answers.
When asked about how database size affects ancestry results, David Nicholson, co-founder of Living DNA, told us, “The tests absolutely rely on the reference database. If you have Polish ancestry but there are no people in the database who are Polish, then what the test will do is show what the next closest group is next to Polish, like German or Eastern European ancestry.” Each ancestry DNA service has its own sample database and reference panel made of the DNA samples collected from their users and information collected from sources like the 1000 Genomes Project. The database consists of all this information collectively. A reference panel is made of certain curated samples with known family history and roots in a specific place. The services use insights gleaned from the reference panel to give you geographical ancestry results. In theory, a larger database leads to more information available to create a good reference panel, which then leads to better results for customers.  
If you are concerned about your data being sold, your concern may be valid. In the past, records have been sold and de-anonymized. It is possible for genetic information to be used to find the name of the individual the DNA came from. This can happen regardless of whether or not your name was in the database. This scenario has occurred in the past.

If you opt in to DNA Relatives, you will be able to send and receive invitations to connect with other customers who share DNA with you. You can choose whether to respond to these invitations or not, and your DNA relatives have the same choice. We cannot guarantee that they will respond to your sharing invitations or messages. Regardless of whether you both agree to share, you will be able to see their birthplace, locations of their ancestors and surnames, if they have chosen to add this information to their profile. If you both accept sharing invitations, you will be able to see ancestry reports and overlapping chromosome segments.

This is one of the most common questions and the most difficult to answer. There are approximately forty companies currently offering DNA testing to determine genealogy and ethnicity. None of these companies have shared their data, no standards of accuracy have been agree on and independent scientists have not yet validated these methods. Some experts believe the results are valid, others feel they must be viewed with some skepticism. Once you receive your results, you must decide on the validity based on your knowledge of your family history.
Whether it’s an autosomal test, a Y-DNA test or an mtDNA test, virtually all providers use the same science. Some providers offer an ‘off the peg’ solution such as Ancestral Origins™ or AncestrybyDNA™, so if you’re interested in these you should shop around for the lowest price. Most providers offer a test that interprets and presents the results in a unique way, so if one of these catches your eye, look for examples of how the results are presented on their website before you buy.