“My concern is that more and more of these tests are being put out, and people are being persuaded to have these tests done, and they get results back that are very often of very low value and dubious helpfulness,” she says. “And often people are told to go to see their GP and that then places a direct stress on the NHS, at no cost to the company. The companies make their profits and walk away, letting the NHS sort out all the fallout, the push-back, from the test results, in a way I find absurd. Why should the NHS have to prop up the problems that these companies create?”
Four testers took 23andMe DNA kits during testing. We received our results 32 days later, and testers were highly satisfied with the overall experience, from ease of sample collection to the thoroughness of the results. Recently, the company updated its database and increased the number of geographic regions from around 170 to more than 1,000. The updated ancestry reports are also more detailed, especially for non-European regions. 23andMe’s ancestry tests give you information split into several different reports spanning your ancestry composition, maternal and paternal haplogroups, neanderthal ancestry and DNA family. Testers particularly liked the timeline feature, which estimates when your most recent ancestor lived in each of your matched regions.
While DNA contains material common to all humans, some portions are unique to each individual. These portions, or regions, contain two genetic types (alleles) that are inherited from the person’s mother and father. A person’s DNA profile is made by investigating a number of these regions. In a paternity test, for example, the mother’s DNA profile is compared with the child’s to find which half was passed on by the mother. The other half of the child’s DNA is then compared with the alleged father’s DNA profile. If they don’t match, the ‘father’ is excluded, which means he isn’t the father of that child. If the DNA profiles match, the ‘father’ is not excluded - which means there is a high probability (more than 99 per cent) that he is the father. DNA tests such as this can’t offer 100 per cent proof.
The test kit gathers saliva from spit. It offers a free family tree tool to which users can contribute their specific results. You can also download your full DNA profile and import that data into another tool -- but it doesn't offer a chromosome browser, so you can't really do DNA segment comparisons. Given this, if you're a true DNA geek, Ancestry may not be the service for you.
Still, it is fun see a visual and numerical representation of where your ancestors came from (generally speaking) and, although there are those who swear by one company or the other, all of these testing companies do a fairly decent job of giving you a report you can enjoy and use in your research. FTNDA recently updated to the much anticipated MyOrigins 2.0 and MyHeritage DNA just updated to their improved 42 population Ethnicity Estimate and offers a nicely detailed report.
If you’d like to take extra measures to provide a means of identifying your DNA in your absence, you can also choose to store your biological DNA sample – this is known as DNA banking. It can provide reassurance to know that a DNA profile can be produced from your securely stored DNA sample, and depending on your circumstances, you can either pay to have your sample stored with the company you purchased it from, or order a home banking kit which will provide the materials you need to securely store your sample at home. If this is of interest, you can check out the companies that offer DNA banking.
As a postscript, I eventually end up having an interesting chat with Titanovo about my “bioinformatics” (distilled from my 23andMe data). One of the first things I’m told is that my eyes are green (they’re brown). However, the bioinformatics got my skin type and frame/weight generally right and had interesting (albeit occasionally generic) things to say about exercise, diet, goals, steering clear of too much sugar and so on.
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— Once you have chosen a test and received your autosomal results there is still a great deal more fun to be had. Independent tools and websites created by scientists and enthusiasts allow you to take the raw data provided from FTDNA, 23andMe and Ancestry DNA and explore them in astounding detail–giving you a wide variety of new admixtures, phasing options, chromosome browsers, SNP tools and connections with family across the world. Gedmatch is our favorite because they have so many wonderful and meticulously updated tools from a variety of sources. Easily upload your raw data and run your results for free (if you love the tools, don’t forget to donate and uncover even more options.)