Admixture percentages are one of the biggest reasons people choose to have their DNA tested. This report attempts to accurately match your DNA with population samples from around the world to tell you where your ancestors came from. Each of these companies has strengths and weaknesses when it comes to this calculation, and in the reports it provides to users.
There's a lot you can learn from a DNA test. In addition to deepening your understanding of ancestry, some services will introduce you to relatives around the world or shed light on your predisposition to specific health issues and diseases. Here we present to you our roundup of the nine top DNA testing kits and services -- what they offer, how they work and how much they cost. 
Went the Southern California Genealogical Society’s June Jamboree, signed up and tried MyHeritageDNA. I know I am Italian and Ukraine/Polish. The Balkans and Baltic showed up but my eastern European ancestry didn’t although Irish, Scottish and Welsh did. No specific location in Italy on my Mom’s side though we still have family there. Their matches weren’t true matches and when I tried to look at the matches’ family trees I would have to spend more money between 3 upgrades. Is this how all these things work? I’m really disappointed in MyHeritage and can’t recommend it for anyone on a fixed income. This is the only one I’ve done but it has left me discouraged.

Living DNA supports 80 geographical ancestry regions, 21 of which are located within Britain and Ireland alone, making it a great DNA test for people wanting to delve deep into their British heritage. Of course, it also covers 60 regions outside of the British Isles, and is expanding its efforts to bring the same level of detail to other world regions.


Early and active treatment of FH can substantially reduce the risk for heart disease. FH treatment focuses on lowering LDL cholesterol levels, and FH is usually treated with cholesterol-lowering medications. Lifestyle modifications, including diet, exercise, and weight control can help lower LDL cholesterol levels. But these changes are generally not enough to effectively manage the condition. In extreme cases of FH, LDL-apheresis, a procedure that filters cholesterol out of the blood, can be used when other treatments have failed.
Health and disease info: DNA testing can also indicate which conditions for which you may have a preponderance. It's a controversial feature, to be sure. Knowing that you have a genetic predisposition to a certain form of cancer may make you more vigilant for testing, but it may also lead to increased stress -- worrying about a potential condition that may never develop, even if you're "genetically susceptible" to it. The possibility of false positives and false negatives abound -- any such information should be discussed with your doctor before you act upon it.

The results came out as half French, 40 % Spanish, some Italian, 1% Sardinian, 1% scottish-Irish. The major problem is that ancient Ibiza DNA has evolved to resemble that of modern French, same thing for Spanish-Valencian DNA: which is shared by modern French people. So if you do have French ancestry, it may show as Spanish and vice versa… THIS GOES FOR EVERYTHING ELSE: IT’S WILL BE VAGUE!
The SGM Plus system of DNA analysis targets ten loci, each of which contains two alleles. These are the “short tandem repeats” that vary between individuals. In addition, a further locus is targeted that acts as in indicator of the sex of the donor. A “full” DNA profile is one in which all of these loci have produced a reliable and reportable result. Occasionally, the processes used to target some of these loci fail, resulting in an incomplete or “partial” DNA profile. The most common reasons for such failure are either that a very small amount of DNA was present in the sample, the DNA may have become degraded, or that substances may have been present in the sample that may have inhibited the analysis process. Depending on the degree of success of the DNA analysis, the match probability calculated from a partial DNA profile may be reduced below the 1 in 1 billion that would be obtained from a full profile.
Early and active treatment of FH can substantially reduce the risk for heart disease. FH treatment focuses on lowering LDL cholesterol levels, and FH is usually treated with cholesterol-lowering medications. Lifestyle modifications, including diet, exercise, and weight control can help lower LDL cholesterol levels. But these changes are generally not enough to effectively manage the condition. In extreme cases of FH, LDL-apheresis, a procedure that filters cholesterol out of the blood, can be used when other treatments have failed.
DNA test companies that use genotyping technology, including 23andMe and Ancestry, allow you to download your raw DNA file. A raw DNA file is usually a text file that contains all the information about your genetic code gleaned from the company’s examination of your DNA. This is comprised of several hundred thousand markers known as SNPs (Single Nucleotide Polymorphisms). Most raw files are organized into five columns: the SNP coded into an rsID number, the chromosome the SNP is located on, the location of the SNP on the chromosome and the two alleles for each SNP.
There are many places you can upload your raw DNA, and several of them are free. Popular third-party DNA analysis tools include GEDmatch and Promethese. GEDmatch is a free, open database and genealogy site that gives additional DNA relative matching and trait results. This tool has information from users of multiple different testing companies. Promethease compares your raw DNA information against scientific reports that link certain markers to health conditions, though you should take these results with a grain of salt as genetic links do not equal a diagnosis.

With autosomal, mitochondrial and Y-DNA genotyping, the Geno 2.0 test examines your ancestry in three time periods, including your Regional Ancestry report, which spans 500 to 10,000 years ago. The test also delves into your Deep Ancestry through your maternal and paternal line haplogroups and you Hominin Ancestry, which tells you how much Neanderthal DNA is hanging out in your genetic code. One quirky but interesting feature explores possible relations to famous geniuses throughout history and estimates how many thousands of years ago you shared a common ancestor with Abraham Lincoln or Charles Darwin.


Product	Price	Overall Rating	Cost	Ancestry Results	Ease of Use	Online Database Features	Upgrade Option	Available Geographic Regions	Database Size	Tester Confidence in Results	Tester Satisfaction Score	Overall Experience Score	Sample Type	Sample Collection and Registration Score	Result Access and Interpretation Score	Turnaround Time (Days)	App	Genetic Relative Connections	Online Family Trees	Upload RAW Data	Download RAW Data

As discussed earlier, in order to determine the ethnicities present in your genetic make-up, genetic ancestry companies can analyse your autosomal DNA to seek out the genetic variants uniquely associated to certain population groups. These groups are known as ‘reference populations’, and they’ve been constructed by sampling the DNA of modern populations around the world, as well as from human remains at various archaeological sites. By identifying these genetic variants in your genetic code, companies can report on the groups that have contributed to your DNA.
Although reference populations are the primary method by which companies calculate your ethnic mix, they don’t represent actual living populations. Instead, they’re a theoretical group who share a unique set of genetic variants, believed to belong to a distinct ethnic group in the past. This is why an ethnicity DNA test will show you that you’re a mix of different ethnicities, instead of placing you in a single ethnic group.
There are many things to think about when deciding whether genetic testing is right for you. Although these tests can provide important information about health risks, they can also be upsetting or raise questions about what the results mean. Genetic tests also have certain limitations that are important to understand. Your personal and family medical history, as well as your goals for testing, should all factor into your decisions about whether and how to test.
It’s worth bearing in mind that when you’re presented with the population groups that have contributed to your DNA, some of the groups revealed may be very general (e.g. Western European) and the report may not tell you when or for how long each group was located in the region that it’s named after. The specificity of the population groups depends on the reference populations used by the company you test with (discussed later). Therefore, if a detailed ethnic breakdown is important to you, look for example reports from the company you’re considering, or get in touch with them to ask for a list of the reference populations that they use.
If you are interested in doing in-depth analysis, the firm offers a chromosome browser, allows raw data to be uploaded, provides support for setting different segment matching thresholds, and allows up to five comparisons to be done at once. Family Tree DNA allows trial transfers from 23andMe and AncestryDNA into its match database; additional transfers of various datasets is available for a fee. The company promises to keep data for 25 years.
The Geno 2.0 test uses a Helix spit-tube test, which is extremely easy to register. It took National Geographic 27 days to notify testers of results. Because Helix uses exome sequencing instead of the more-common genotyping, you cannot download your raw DNA information from this test to upload into other databases. You can, however, purchase more DNA apps from the Helix Marketplace to run your data through partner databases without submitting additional samples.
The Y chromosome is a special chromosome, passed on from fathers to their sons, while mothers pass on mtDNA to both their sons and daughters. But mtDNA dies with men and so it survives only in the female line. This means that a man’s lineage can be followed along both paternal and maternal lines, while in a woman only her maternal or mtDNA line can be followed.
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