DNA fingerprinting is commonly used to compare DNA samples taken from the crime scene with those taken from suspects, to either prove or disprove their innocence. In the UK, 10 markers are analysed to produce DNA profiles from the samples taken in criminal investigations. These are then compared to (and stored in) the National DNA Database (NDNAD) to identify if there’s a match. This database currently contains DNA profiles for 10% of the UK population, along with the individuals’ names and ethnicities. Anyone who’s been arrested for a recordable offence has their information recorded on the database, unless they are found innocent or not charged – in these cases, the individuals’ biological samples and corresponding information is destroyed within six months of sample collection.
Early and active treatment of FH can substantially reduce the risk for heart disease. FH treatment focuses on lowering LDL cholesterol levels, and FH is usually treated with cholesterol-lowering medications. Lifestyle modifications, including diet, exercise, and weight control can help lower LDL cholesterol levels. But these changes are generally not enough to effectively manage the condition. In extreme cases of FH, LDL-apheresis, a procedure that filters cholesterol out of the blood, can be used when other treatments have failed.
As stated at the start of this guide, each one of the main tests will provide you with easy-to-use reports and cousin matching that you can use in your genealogy research. You will need to carefully review the information provided in this guide to make a decision about which test is best for your particular needs. You may also choose to test with (or upload your results to) multiple companies.

Newman says that there’s a basic lack of “literacy” and understanding about genetic testing, among the public and even other health professionals. People are given false reassurances or made to panic (just because you have certain genetic variants, it doesn’t mean that you will develop a particular condition). Newman also makes the point that, in his field, counselling happens before and after testing and, while people with cancer or heart issues nearly always opt to have the test (as they can then take action to varying degrees), often people with conditions such as Huntington’s disease in their family decide not to go ahead because a diagnosis would change nothing for them. In any event, Newman says that, with genetic testing, while there are different levels, intensive counselling is always “absolutely key”.
1. Family Tree DNA’s Family Finder: One of the first to offer these types of tests, FTDNA is generally considered the leader in autosomal DNA testing for ancestry and provides some of the best tools available for genealogists. Their population finder section is currently a bit less specific than the other companies, but FTDNA Family Finder users are eagerly awaiting a much improved update to be released sometime in the next month. Find out about Family Finder here.
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