Still, it is fun see a visual and numerical representation of where your ancestors came from (generally speaking) and, although there are those who swear by one company or the other, all of these testing companies do a fairly decent job of giving you a report you can enjoy and use in your research. FTNDA recently updated to the much anticipated MyOrigins 2.0 and MyHeritage DNA just updated to their improved 42 population Ethnicity Estimate and offers a nicely detailed report.
The Geno 2.0 test uses a Helix spit-tube test, which is extremely easy to register. It took National Geographic 27 days to notify testers of results. Because Helix uses exome sequencing instead of the more-common genotyping, you cannot download your raw DNA information from this test to upload into other databases. You can, however, purchase more DNA apps from the Helix Marketplace to run your data through partner databases without submitting additional samples.
Every human carries two copies of the genetic code, one inherited from the mother and one from the father, some 6 billion letters in all. Apart from identical twins, no two individuals have the same genetic code. With the exception of the egg and sperm cells, all the cells of our bodies have 23 pairs of chromosomes, 46 in all. One chromosome of the pair is inherited from the father and one from the mother. However, in males the 23rd pair consists of a so-called Y-chromosome and an X-chromosome, whereas females have two X-chromosomes. The Y chromosome contains a gene which triggers embryonic development as a male and carries information about the male’s paternal lineage.
So, back to the example of the two men (lets call them John and James) we think might be brothers: We find two g-g-grandsons (or any male descendant in a direct father-son line) of each, preferably the most distant cousins we can find, and get a Y-DNA test done for all four men. Usually a 37 marker Y-DNA test is a good place to start. This looks at 37 sections of each persons DNA that the genetic scientists think are most useful for our purposes (the bits that are least likely to randomly change over generations). The results come back looking like a fairly meaningless string of numbers which are fairly useless on their own, but allow us to compare each persons result with others in the database of the testing company.
If you're creeped out by how much information Facebook, Google and Amazon have on you based on your online browsing habits, just remember that these DNA testing services are getting what is effectively your medical history. Make sure of their policies before turning over that valuable data. Also, even if you don't share your DNA with a service, your familial DNA data may be available if a relative shared their genetic material. The privacy issues can get very complex.
Most of the services we tested use genotyping to read your DNA. Genotyping looks for specific markers in your genetic code. For something like ancestry testing, genotyping is effective because it identifies known variants in your DNA. Scientifically speaking, genotyping’s weakness is that it can only recognize previously identified markers. This is one reason DNA tests’ accuracy relies so heavily on the DNA database size; there must be enough information available and identified genetic variants in the database to recognize new customers’ markers.
If you’d like to take extra measures to provide a means of identifying your DNA in your absence, you can also choose to store your biological DNA sample – this is known as DNA banking. It can provide reassurance to know that a DNA profile can be produced from your securely stored DNA sample, and depending on your circumstances, you can either pay to have your sample stored with the company you purchased it from, or order a home banking kit which will provide the materials you need to securely store your sample at home. If this is of interest, you can check out the companies that offer DNA banking.
AncestryDNA has been responsible for taking DNA testing mainstream, and they now have the world’s largest autosomal DNA database. The test benefits from a number of innovative and sophisticated features such as shaky leaf DNA hints integrated with family trees, DNA Circles, Genetic Communities and New Ancestor Discoveries. A subscription is required to access some of these features and to view the full trees of your matches. The lack of a chromosome browser and matching segment data is a big disadvantage for advanced users who are interested in chromosome mapping. Many of the people now taking the AncestryDNA test are lured in by the biogeographical ancestry reports, but are not interested in communicating about genealogy. However, the test is encouraging an interest in genealogy in a subset of this market.
Rather than simply looking at your DNA in isolation, the Findmypast DNA test analyses unique combinations of linked DNA. This proprietary method delivers a level of detail impossible with other ancestry DNA tests. It also uses the latest technology, which is constantly updated in response to the latest industry innovations and peer-reviewed research. As the technology evolves so too does the detail of your test results, which will receive free ongoing upgrades.
This report tells you interesting information, such as that your DNA relatives are 32 percent more likely to own a cat or 11 percent less likely to have lived near a farm when they were young. DNA Passport by Humancode offers information about more than 20 physical traits, from appearance to grip strength. Ancestry DNA recently added its AncestryDNA Traits upgrade for $10, and it lets customers who have already taken one of its tests unlock information about 18 genetically influenced traits, including bitter taste perception, freckles and cilantro aversion.
ARSACS Agenesis of the Corpus Callosum with Peripheral Neuropathy Autosomal Recessive Polycystic Kidney Disease Beta Thalassemia and Related Hemoglobinopathies Bloom Syndrome Canavan Disease Congenital Disorder of Glycosylation Type 1a (PMM2-CDG) Cystic Fibrosis D-Bifunctional Protein Deficiency Dihydrolipoamide Dehydrogenase Deficiency Familial Dysautonomia Familial Hyperinsulinism (ABCC8-Related) Familial Mediterranean Fever Fanconi Anemia Group C GRACILE Syndrome Gaucher Disease Type 1 Glycogen Storage Disease Type Ia Glycogen Storage Disease Type Ib Hereditary Fructose Intolerance Herlitz Junctional Epidermolysis Bullosa (LAMB3-Related) Leigh Syndrome, French Canadian Type Limb-Girdle Muscular Dystrophy Type 2D Limb-Girdle Muscular Dystrophy Type 2E Limb-Girdle Muscular Dystrophy Type 2I MCAD Deficiency Maple Syrup Urine Disease Type 1B Mucolipidosis Type IV Neuronal Ceroid Lipofuscinosis (CLN5-Related) Neuronal Ceroid Lipofuscinosis (PPT1-Related) Niemann-Pick Disease Type A Nijmegen Breakage Syndrome Nonsyndromic Hearing Loss and Deafness, DFNB1 (GJB2-Related) Pendred Syndrome and DFNB4 Hearing Loss (SLC26A4-Related) Phenylketonuria and Related Disorders Primary Hyperoxaluria Type 2 Rhizomelic Chondrodysplasia Punctata Type 1 Salla Disease Sickle Cell Anemia Sjögren-Larsson Syndrome Tay-Sachs Disease Tyrosinemia Type I Usher Syndrome Type 1F Usher Syndrome Type 3A Zellweger Syndrome Spectrum (PEX1-Related)
Testers appreciated the amount of information and context given with each report. For example, the regional ancestry report matches your DNA to broad world regions on a map, but it also compares your DNA to two more-specific reference populations. My regions were Northeastern Asia and South China Sea, which fit the Korean and Japanese reference populations. Another tester was matched to 11 geographic regions throughout Europe, North America and West Asia, and they were matched to Argentinian and Puerto Rican reference populations.
I have tried Ancestry and 23 and me.Ancestry is great for their database and forming a family tree and their DNA matches are good.I liked 23 and me the best as I thought the results on my heritage matched more what I know to be true of my Northern European background.They gave me 10% more Scandinavian which my father was .I have found no one from the Iberian peninsula going back to the 1400’s on the Ancestry database yet they tell me I have 9% from that arena ,but 23 and me says only 2% which I believe is more accurate.
AncestryDNA recently updated their service, adding new regions and adjusting their algorithm to make their ethnicity estimates more accurate. You're not alone in being a bit bewildered, since plenty of people have had their results change unexpectedly. As genetic ancestry analysis is a relatively recent science and is improving all the time, your results will become more accurate as more people enter the Ancestry database, allowing them to hone their algorithm accordingly.
Finally, if you happen to meet a special someone on DNA Romance and want to see what your future child together might look like, there’s BabyGlimpse by HumanCode. Like a very advanced Punnett square, BabyGlimpse compares your and your partner’s DNA to create a profile that examines which traits your offspring might inherit, including things like ancestral DNA, eye color and lactose intolerance.
— Once you have chosen a test and received your autosomal results there is still a great deal more fun to be had. Independent tools and websites created by scientists and enthusiasts allow you to take the raw data provided from FTDNA, 23andMe and Ancestry DNA and explore them in astounding detail–giving you a wide variety of new admixtures, phasing options, chromosome browsers, SNP tools and connections with family across the world. Gedmatch is our favorite because they have so many wonderful and meticulously updated tools from a variety of sources. Easily upload your raw data and run your results for free (if you love the tools, don’t forget to donate and uncover even more options.)