I recommend one of two options. It may cost a little more, but I would highly recommend saving the extra and using DNA Tribes® rather than spending over half the cost for minimal tribal/biogeographical pinpointed information. The primary benefit of STR rather than SNP testing is the availability of rich reference data. DNA Tribes® tests industry standard autosomal STR systems, which allow the identification of a person’s DNA profile not shared with any other person. Because these STR markers have been tested and used in the court systems around the world, they allow DNA Tribes® to perform the most thorough comparison of a person’s own DNA profile to over 1,200 ethnic groups (populations) around the world. At present, SNP testing from these other autosomnal DNA testing kits does not yet match the geographical detail of DNA Tribes® autosomal STR analysis.
Once your genetic information is out there, it’s difficult to undo. Also, once you know something about yourself, it’s impossible to un-know. Revelations such as having different parents than you expected or finding unknown half-siblings are difficult to process at any age, but it’s particularly troubling for kids. However, you can always simply opt out of family matching features.
With over 10 million samples in its database, AncestryDNA is one of the largest players in the consumer DNA testing industry. Its DNA ancestry test paired with its extensive genealogical data from family trees and historical records makes Ancestry the perfect destination for a holistic view of your family history. Getting the most out of your AncestryDNA results requires a bit of work, as the DNA test works best in concert with the site’s other available resources. You can use the DNA service without creating a family tree, though the results are much less interesting. Ancestry uses information gleaned from its user’s DNA and family trees to create compelling stories about your family’s recent history and migrations. Testers with European roots could trace their family’s movements across the Atlantic and see what stops they made on their way across the U.S. I took the AncestryDNA test in 2016 and was disappointed by my initial report, which put my results into a giant area encompassing at least 15 countries labeled “Asia East.” Since then, Ancestry has updated its algorithm and reference population to make its results more specific, but it still only supports 17 regions in Asia and West Asia compared to 296 regions in Europe. Our testers received results from Ancestry 35 days after dropping their tubes of spit in the mail. We generally liked the company’s website and found the interface easy-to-use and navigate. While Ancestry does allow you to download your raw DNA data, it does not allow you to upload raw data from tests taken through other companies.
If you are concerned about your data being sold, your concern may be valid. In the past, records have been sold and de-anonymized. It is possible for genetic information to be used to find the name of the individual the DNA came from. This can happen regardless of whether or not your name was in the database. This scenario has occurred in the past.
All this comes into sharp focus with the comprehensive kits such as the one provided by 23andMe: the one I drool into a tube for (incidentally, 23andMe doesn’t test for Huntington’s disease). Most people, like myself, have a low understanding of genetic variants, what phrases such as “higher risk” or “probability” actually mean or how to interpret our results correctly. Is it right that ordinary members of the public must navigate potentially frightening and/or misleading results alone?
DNA Clinics will always advise an appointment for your DNA test. However, there are occasions and circumstances when our customers prefer to collect their own mouth swab samples for DNA testing. DNA Clinics self-collection DNA testing kits are available to order by telephone by calling 0800 988 7107 or on-line at www.homednapaternitytest.co.uk. DNA test kits ordered on-line are sent out for FREE. The payment for your chosen DNA test is payable when you return your samples to DNA Clinics.
On all platforms except for National Geographic, you can initiate a search for relatives, though some services let you upload your National Geographic results for further analysis. The software continually searches for DNA matches as more people share their results. This feature may be useful if you're building a family tree or looking for relatives you've never met; otherwise, it may more of a nuisance. You can opt in or out at any time, and the DNA service doesn't share your contact information. Relatives can message you through the software, though. If you already use genealogy software, you may be able to download your results and upload them into your preferred program. Otherwise, AncestryDNA and others featured here have family tree software that you can easily link.
A few of the DNA tests we tested, including the National Geographic Geno 2.0, use genetic sequencing instead of genotyping. Sequencing is newer in the mainstream direct-to-consumer DNA testing market, as it used to cost more and take much longer to sequence a person’s DNA. Sequencing identifies the exact makeup of a certain piece of DNA – be it a short segment or the whole genome. The Helix tests sequence the Exome, which are the parts of the genome responsible for protein production, plus several other regions of interest. DNA sequencing gives more information overall and has more uses in medical testing than genotyping. In the future, more DNA kits may move from genotyping to DNA sequencing as the technology gets cheaper and faster, but for now both are effective ways to look into your geographic ancestry.
A DNA paternity test can answer a multitude of questions. Which is why when deciding to get a DNA paternity test, the purpose should be carefully considered. A DNA paternity test for peace of mind, where the samples are collected at home, cannot be used for legal purposes. The added expense of maintaining the strict chain of custody required for legal testing, where samples are taken at an authorised collection centre, may not be necessary.
Health & Wellness tests: There are a ton of health and wellness DNA tests. We found several specifically oriented to dieting and weight loss, including embodyDNA, Vitagene, DNAFit and the several options available through the Helix marketplace. While there definitely are some links between DNA and factors that contribute to weight, we advise taking these diet plans with a grain of salt, as DNA science is still a relatively young field. We similarly advise caution for the multitude of non-diet health and wellness DNA tests, which offer insights into your sleep, food sensitivities, and vitamin and mineral levels. And double that for medical information found in consumer DNA kit test results. While medical insights learned from taking an at-home DNA test may be interesting, it’s best not to take them too seriously. If you have a concern about a genetic predisposition to a disease, it’s best to talk to your doctor instead of relying on a direct-to-consumer kit.
Which is all very well, but do these kits work and deliver the service they promise and what about the wider ethics and implications of home genetic testing? Is it always wise for generally under-informed, under-prepared consumers to meddle in the highly complex, nuanced arena of genetics, risking confusion, complacency or even outright panic and anxiety when confronted with ostensible “bad news” (which may not even be true)?