In Newman’s view, the genie is out of the bottle with home genetic-testing kits. He says that while the kits could potentially provide data in the future, right now, they lack “clinical utility” – they look at genetic variants that, individually, have a very low chance of predicting specific health risks, as there are too many variables: “It’s like the Opportunity Knocks clap-o-meter, with some people further along the scale, and therefore more likely to get the condition and then people at the other end of the scale, who are unlikely to get it.”
I sadly have to agree as after the results appeared in my Ancestry account I was very disappointed to see that they failed to disclose any sign of my Italian heritage at all and even clicking through the Engilsh ethnic breakdown showed absolutely NO connection to any place whatsoever so apparently I am an alien who was dropped here from outer space so I could not recommend this as a service that produces a valid ethnic breakdown at all. Their results graph and click through breakdown are extremely limited, especially after comparing them with other services so from the ethnicity perspective, think they are bordering on false advertising!!
In addition to showing geographic ancestry percentages, some direct-to-consumer DNA tests also include insights about physical traits like hair and eye color. With 23andMe, this trait information is mostly available in the upgraded Ancestry + Health kit, but some interesting tidbits can be found in the Your DNA Family report, which is available if you opt to participate in the DNA Relatives service. This report tells you interesting information, such as that your DNA relatives are 32 percent more likely to own a cat or 11 percent less likely to have lived near a farm when they were young. DNA Passport by Humancode offers information about more than 20 physical traits, from appearance to grip strength. Ancestry DNA recently added its AncestryDNA Traits upgrade for $10, and it lets customers who have already taken one of its tests unlock information about 18 genetically influenced traits, including bitter taste perception, freckles and cilantro aversion.
There is a TV show called Long Lost Family on TLC that uses Ancestry DNA and records to identify and locate families. I am not an adoptee but have taken tests with Ancestry and Family Tree DNA. I think using the Ancestry test would be better to help identify your birth parents since you could view your close matches and their family trees (if public). You can also download the raw data from Ancestry, FamilyTree, or 23&Me and upload them to gedmatch. Gedmatch is a free site where test-takers from different companies can compare results/matches without having to test with all three companies.
The 100,000 Genomes Project is an NHS initiative, run by Genomics England, and is the largest national genome sequencing project in the world. On entering, patients have their entire genome, of more than 3bn base pairs, sequenced. This is different from commercially available genetic testing kits, such as those from 23andMe, which only look at very small stretches of DNA in a process called genotyping. The hope of the NHS is that having so much genetic information, from so many different people, will allow “groundbreaking discoveries about how diseases work, who could be susceptible to them, how we can treat them, and what treatments might work”.
Most ancestry DNA kits cost about $100. AncestryDNA, 23andMe’s Ancestry test and National Geographic’s Geno 2.0 test all fall nicely into that price point. If you’re looking for a bargain, we recommend waiting to buy until your preferred test is on sale, as they’re often available well below their usual price. To get the most for your money, buy an Ancestry or 23andMe kit on sale then upload your raw data to MyHeritage DNA’s database, which is free.
If you’re already using a specific geneology program, use their DNA test. I used My Heritage while I was using Ancestry for my family tree. I got called by a high pressure salesman to sign up for the My Heritage geneology program. (I had uploaded my gedcom to the My Heritage site.) I told him that I couldn’t afford two geneology sites. The guy was snotty and condescending. We figure we just wasted our money with My Heritage and will do the Ancestry DNA as soon as we can afford it.
A DNA paternity test can answer a multitude of questions. Which is why when deciding to get a DNA paternity test, the purpose should be carefully considered. A DNA paternity test for peace of mind, where the samples are collected at home, cannot be used for legal purposes. The added expense of maintaining the strict chain of custody required for legal testing, where samples are taken at an authorised collection centre, may not be necessary.
Whether it’s an autosomal test, a Y-DNA test or an mtDNA test, virtually all providers use the same science. Some providers offer an ‘off the peg’ solution such as Ancestral Origins™ or AncestrybyDNA™, so if you’re interested in these you should shop around for the lowest price. Most providers offer a test that interprets and presents the results in a unique way, so if one of these catches your eye, look for examples of how the results are presented on their website before you buy.